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Relieve Pain. Restore Life.

Post-amputation pain control with the press of a button

At last, there’s an on-demand treatment option that is non-addictive, non-toxic, and provides lasting relief.

The Altius® System

The Altius Direct Electrical Nerve Stimulation System is FDA-approved to help adults living with lower
limb loss who have chronic post-amputation pain, such as phantom limb pain or residual limb pain.
This patient-controlled, implanted electrical stimulation device gives you the power to start treatments
when you need them.

Altius works directly at the source of pain.

What Causes
Post-Amputation Pain?

Amputation damages nerve endings in your leg.

Damaged nerves become hyperactive and send more pain signals to your brain…

…causing frequent and severe pain.

80% of patients may experience post-amputation pain, like phantom limb pain or residual limb pain.1

How The Altius System Works.

The Altius System delivers electrical stimulation directly to the damaged nerves.

This helps prevent pain signals from reaching your brain…

…resulting in rapid and lasting pain relief.

Pain control in the palm of your hand.

Altius can be implanted by a trained physician, typically as a same-day procedure. Using a handheld remote,
you can choose when to activate Altius and manage your pain.

1. Altius Implantable Pulse Generator

Sends electrical stimulation to the damaged nerve endings

2. Cuff Electrode

Secured around damaged nerve

Altius Implantable Pulse Generator

Altius Patient Controller

Controls pain with the press of a button

Altius Patient Controller

Carefully studied.
Clinically proven.

In a clinical study2, patients treated with the Altius System reported:

Pain Reduction

50% Reduction in pain*

Lasting Relief

Continued improvement in daily pain levels through 12 months

Opioid Reduction

81% of patients taking opioids decreased or eliminated opioid use

Quality of Life

45% improvement in quality of life

* Patients in the clinical study started therapy with Altius upon feeling pain. Patients averaged ~30% reduction in pain 30 minutes after starting a session and ~50% reduction in pain 120 minutes after starting a session.

Life Changing Results

Hear from a real Altius patient

It’s Time to Take Control Over the Pain

Contact us to stay updated on the availability of Altius

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1. Hsu E, Cohen SP. Postamputation pain: epidemiology, mechanisms, and treatment. J Pain Res. 2013.

2. Kapural L, Kim B, Eidt J, et al. Long-term treatment of chronic post-amputation pain with bioelectric nerve block: 12-month results of the randomized, doubled-blinded, crossed-over QUEST study. Neuromodulation. 2024. 180 patients were enrolled in the clinical study. Individual patient outcomes may vary.

Indications for Use: The Altius® Direct Electrical Nerve Stimulation System is indicated as an aid in the management of chronic intractable phantom and residual lower limb post-amputation pain in adult amputees. Contraindications: The Altius system is contraindicated for patients who are: Unable to operate the system or Unsuitable for the Altius implant surgery. Warnings/Precautions: Use as indicated and instructed. Diathermy should not be used on patients with the Altius System, or any of its components, either as a treatment for a medical condition or as part of a surgical procedure. Electromagnetic interference (EMI) is a field of energy generated by equipment found in the home, work, medical, or public environments that is strong enough to interfere with Altius system function. The electrical pulses from the Altius system may interact with the sensing operation from a cardiac device and could result in an inappropriate response of the cardiac device; physicians involved should discuss the possible interactions between the devices before surgery. Safety and Effectiveness of Altius System for pediatric use and for pregnant patients has not been established. Surgical complications and adverse events may be more frequent and severe in diabetic patients. Safety of MRI/NMRI with an implanted Altius system has not been evaluated. Patients implanted with the Altius System, or any of its components, should not be subject to MRI/NMRI. See Instructions for Use for detailed information regarding the procedure(s), indications, contraindications, warnings, precautions, and potential adverse events. For further information and to view full Instructions for Use, visit www.neurosmedical.com.

Although FDA has determined that the probable benefits outweigh the probable risks, there remains some uncertainty regarding the manufacturer’s human factors engineering (HFE) and usability engineering (UE) analysis and validation testing. As a condition of approval, FDA is requiring the manufacturer to provide an HFE/UE analysis and validation testing and recommending that this analysis and testing is designed using the FDA’s 2016 guidance document “Applying Human Factors and Usability Engineering to Medical Devices” (https://www.fda.gov/media/80481/download).

This information is for informational purposes only, is not medical advice or a diagnosis, and is not a substitute for professional medical advice. Consult with your doctor regarding your condition. Individual symptoms, circumstances, and results vary.